BDBM50416266 CHEMBL1082722

SMILES: Cc1ccc(s1)C(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1

InChI Key: InChIKey=MALNQGDQKFOVDK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50416266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416266 (CHEMBL1082722) Show SMILES Cc1ccc(s1)C(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1 Show InChI InChI=1S/C19H19N3O2S/c1-12-5-3-6-14(11-12)17-20-18(24-21-17)15-7-4-10-22(15)19(23)16-9-8-13(2)25-16/h3,5-6,8-9,11,15H,4,7,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416266 (CHEMBL1082722) Show SMILES Cc1ccc(s1)C(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1 Show InChI InChI=1S/C19H19N3O2S/c1-12-5-3-6-14(11-12)17-20-18(24-21-17)15-7-4-10-22(15)19(23)16-9-8-13(2)25-16/h3,5-6,8-9,11,15H,4,7,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium level				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair