BDBM50416270 CHEMBL1082976

SMILES: Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)C1CCCC1

InChI Key: InChIKey=JZKLCRLGOXZBRB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50416270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50416270 (CHEMBL1082976) Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)C1CCCC1 Show InChI InChI=1S/C18H22ClN5O/c19-14-8-5-9-15(12-14)24-21-17(20-22-24)16-10-3-4-11-23(16)18(25)13-6-1-2-7-13/h5,8-9,12-13,16H,1-4,6-7,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50416270 (CHEMBL1082976) Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)C1CCCC1 Show InChI InChI=1S/C18H22ClN5O/c19-14-8-5-9-15(12-14)24-21-17(20-22-24)16-10-3-4-11-23(16)18(25)13-6-1-2-7-13/h5,8-9,12-13,16H,1-4,6-7,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium level				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair