null

SMILES: COCC(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1

InChI Key: InChIKey=JZLUAPQUEFOVBU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50416277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416277 (CHEMBL1082635) Show SMILES COCC(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1 Show InChI InChI=1S/C16H19N3O3/c1-11-5-3-6-12(9-11)15-17-16(22-18-15)13-7-4-8-19(13)14(20)10-21-2/h3,5-6,9,13H,4,7-8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50416277 (CHEMBL1082635) Show SMILES COCC(=O)N1CCCC1c1nc(no1)-c1cccc(C)c1 Show InChI InChI=1S/C16H19N3O3/c1-11-5-3-6-12(9-11)15-17-16(22-18-15)13-7-4-8-19(13)14(20)10-21-2/h3,5-6,9,13H,4,7-8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium level				Bioorg Med Chem Lett 20: 3737-41 (2010) Article DOI: 10.1016/j.bmcl.2010.04.075 BindingDB Entry DOI: 10.7270/Q2FX7BPQ
					More data for this Ligand-Target Pair