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SMILES: Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)c1ccco1

InChI Key: InChIKey=VAFJSTKTOICXIQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416279   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50416279
PNG
(CHEMBL1084476)
Show SMILES Clc1cccc(c1)-n1nnc(n1)C1CCCCN1C(=O)c1ccco1
Show InChI InChI=1S/C17H16ClN5O2/c18-12-5-3-6-13(11-12)23-20-16(19-21-23)14-7-1-2-9-22(14)17(24)15-8-4-10-25-15/h3-6,8,10-11,14H,1-2,7,9H2
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Similars
Article
PubMed
 126n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranes

Bioorg Med Chem Lett 20: 3737-41 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.075
BindingDB Entry DOI: 10.7270/Q2FX7BPQ
More data for this
Ligand-Target Pair