BDBM50416611 CHEMBL1222519

SMILES: Fc1ccc(CNC(=O)[C@@H]2CCC(=O)N2C2CCCC2)c(Cl)c1

InChI Key: InChIKey=BRNWIGMTPZPLKS-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416611 (CHEMBL1222519) Show SMILES Fc1ccc(CNC(=O)[C@@H]2CCC(=O)N2C2CCCC2)c(Cl)c1 |r| Show InChI InChI=1S/C17H20ClFN2O2/c18-14-9-12(19)6-5-11(14)10-20-17(23)15-7-8-16(22)21(15)13-3-1-2-4-13/h5-6,9,13,15H,1-4,7-8,10H2,(H,20,23)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay				Bioorg Med Chem Lett 20: 5080-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T
					More data for this Ligand-Target Pair