BDBM50416870 CHEMBL1257221

SMILES: COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)c(C)noc2=O)C(F)(F)F

InChI Key: InChIKey=ZVCDNODZUJDLPU-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50416870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50416870 (CHEMBL1257221) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)c(C)noc2=O)C(F)(F)F Show InChI InChI=1S/C23H24F4N2O4/c1-13-17-10-15(6-7-16(17)20(30)33-29-13)28-12-22(31,23(25,26)27)11-21(2,3)18-9-14(24)5-8-19(18)32-4/h5-10,28,31H,11-12H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Schering Pharma AG Curated by ChEMBL					Assay Description Binding affinity to human recombinant androgen receptor expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 5835-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.125 BindingDB Entry DOI: 10.7270/Q26974V3
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50416870 (CHEMBL1257221) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)c(C)noc2=O)C(F)(F)F Show InChI InChI=1S/C23H24F4N2O4/c1-13-17-10-15(6-7-16(17)20(30)33-29-13)28-12-22(31,23(25,26)27)11-21(2,3)18-9-14(24)5-8-19(18)32-4/h5-10,28,31H,11-12H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Schering Pharma AG Curated by ChEMBL					Assay Description Binding affinity to human recombinant mineralocorticoid receptor expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 5835-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.125 BindingDB Entry DOI: 10.7270/Q26974V3
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50416870 (CHEMBL1257221) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)c(C)noc2=O)C(F)(F)F Show InChI InChI=1S/C23H24F4N2O4/c1-13-17-10-15(6-7-16(17)20(30)33-29-13)28-12-22(31,23(25,26)27)11-21(2,3)18-9-14(24)5-8-19(18)32-4/h5-10,28,31H,11-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Schering Pharma AG Curated by ChEMBL					Assay Description Binding affinity to human recombinant progesterone receptor expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 5835-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.125 BindingDB Entry DOI: 10.7270/Q26974V3
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416870 (CHEMBL1257221) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)c(C)noc2=O)C(F)(F)F Show InChI InChI=1S/C23H24F4N2O4/c1-13-17-10-15(6-7-16(17)20(30)33-29-13)28-12-22(31,23(25,26)27)11-21(2,3)18-9-14(24)5-8-19(18)32-4/h5-10,28,31H,11-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Schering Pharma AG Curated by ChEMBL					Assay Description Binding affinity to human recombinant glucocorticoid receptor expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 5835-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.125 BindingDB Entry DOI: 10.7270/Q26974V3
					More data for this Ligand-Target Pair