BDBM50417835 CHEMBL1669384

SMILES: CCCn1ccc2cc(OCc3cccnc3)cc(Cl)c2c1=O

InChI Key: InChIKey=UTAIQGDGWVABPF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417835 (CHEMBL1669384) Show SMILES CCCn1ccc2cc(OCc3cccnc3)cc(Cl)c2c1=O Show InChI InChI=1S/C18H17ClN2O2/c1-2-7-21-8-5-14-9-15(10-16(19)17(14)18(21)22)23-12-13-4-3-6-20-11-13/h3-6,8-11H,2,7,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair