BDBM50417841 CHEMBL1669387

SMILES: CCCn1ccc2cc(OCCCc3cccnc3)cc(Cl)c2c1=O

InChI Key: InChIKey=DYMLLWBQOOGYRB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50417841 (CHEMBL1669387) Show SMILES CCCn1ccc2cc(OCCCc3cccnc3)cc(Cl)c2c1=O Show InChI InChI=1S/C20H21ClN2O2/c1-2-9-23-10-7-16-12-17(13-18(21)19(16)20(23)24)25-11-4-6-15-5-3-8-22-14-15/h3,5,7-8,10,12-14H,2,4,6,9,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Agonist activity at human mGluR2 expressed in CHO cells at by [S35]GTPgammaS binding assay				Bioorg Med Chem Lett 21: 971-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.048 BindingDB Entry DOI: 10.7270/Q2JD4Z18
					More data for this Ligand-Target Pair