Found 4 hits for monomerid = 50418154 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM50418154
(CHEMBL1760417)Show SMILES CCCCN(c1cc(ccc1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H32ClNO5S/c1-6-7-16-30(25-17-23(9-8-18(25)2)22-10-12-24(29)13-11-22)36(33,34)27-15-14-26(19(3)20(27)4)35-21(5)28(31)32/h8-15,17,21H,6-7,16H2,1-5H3,(H,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARgamma by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50418154
(CHEMBL1760417)Show SMILES CCCCN(c1cc(ccc1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H32ClNO5S/c1-6-7-16-30(25-17-23(9-8-18(25)2)22-10-12-24(29)13-11-22)36(33,34)27-15-14-26(19(3)20(27)4)35-21(5)28(31)32/h8-15,17,21H,6-7,16H2,1-5H3,(H,31,32) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 794 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Partial agonist activity at human PPARdelta expressed in african green monkey CV1 cells transfected with Gal4 assessed as beta-galactosidase activity... |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50418154
(CHEMBL1760417)Show SMILES CCCCN(c1cc(ccc1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H32ClNO5S/c1-6-7-16-30(25-17-23(9-8-18(25)2)22-10-12-24(29)13-11-22)36(33,34)27-15-14-26(19(3)20(27)4)35-21(5)28(31)32/h8-15,17,21H,6-7,16H2,1-5H3,(H,31,32) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARdelta by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50418154
(CHEMBL1760417)Show SMILES CCCCN(c1cc(ccc1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H32ClNO5S/c1-6-7-16-30(25-17-23(9-8-18(25)2)22-10-12-24(29)13-11-22)36(33,34)27-15-14-26(19(3)20(27)4)35-21(5)28(31)32/h8-15,17,21H,6-7,16H2,1-5H3,(H,31,32) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARalpha by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |