BDBM50419209 CHEMBL1835899

SMILES: CC(C)CN(CC(=O)Nc1cc(F)cc(F)c1)C(=O)c1ccc(cc1)-c1ccccn1

InChI Key: InChIKey=NQCSFWCJFQDXCF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50419209 (CHEMBL1835899) Show SMILES CC(C)CN(CC(=O)Nc1cc(F)cc(F)c1)C(=O)c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C24H23F2N3O2/c1-16(2)14-29(15-23(30)28-21-12-19(25)11-20(26)13-21)24(31)18-8-6-17(7-9-18)22-5-3-4-10-27-22/h3-13,16H,14-15H2,1-2H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GlyT1 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay				Bioorg Med Chem Lett 21: 6176-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.096 BindingDB Entry DOI: 10.7270/Q2251KF6
					More data for this Ligand-Target Pair