BDBM50419233 CHEMBL1835890

SMILES: Fc1cc(F)cc(NC(=O)CN(C2CCCCC2)C(=O)c2ccc(cc2)N2CCCC2)c1

InChI Key: InChIKey=AOMIINKUZDISBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50419233 (CHEMBL1835890) Show SMILES Fc1cc(F)cc(NC(=O)CN(C2CCCCC2)C(=O)c2ccc(cc2)N2CCCC2)c1 Show InChI InChI=1S/C25H29F2N3O2/c26-19-14-20(27)16-21(15-19)28-24(31)17-30(23-6-2-1-3-7-23)25(32)18-8-10-22(11-9-18)29-12-4-5-13-29/h8-11,14-16,23H,1-7,12-13,17H2,(H,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GlyT1 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay				Bioorg Med Chem Lett 21: 6176-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.096 BindingDB Entry DOI: 10.7270/Q2251KF6
					More data for this Ligand-Target Pair
Glycine transporter 2 (Homo sapiens (Human))	BDBM50419233 (CHEMBL1835890) Show SMILES Fc1cc(F)cc(NC(=O)CN(C2CCCCC2)C(=O)c2ccc(cc2)N2CCCC2)c1 Show InChI InChI=1S/C25H29F2N3O2/c26-19-14-20(27)16-21(15-19)28-24(31)17-30(23-6-2-1-3-7-23)25(32)18-8-10-22(11-9-18)29-12-4-5-13-29/h8-11,14-16,23H,1-7,12-13,17H2,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GlyT2 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay				Bioorg Med Chem Lett 21: 6176-9 (2011) Article DOI: 10.1016/j.bmcl.2011.07.096 BindingDB Entry DOI: 10.7270/Q2251KF6
					More data for this Ligand-Target Pair