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SMILES: CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)cc4cc(oc34)C(C)C)n2)cc1

InChI Key: InChIKey=XDMJIJUZTBXYQQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419396   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50419396
PNG
(CHEMBL1915246)
Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)cc4cc(oc34)C(C)C)n2)cc1
Show InChI InChI=1S/C25H27ClN4O2/c1-15(2)23-12-18-10-20(26)11-19(24(18)32-23)14-30-16(3)9-22(29-30)25(31)28-21-7-5-17(6-8-21)13-27-4/h5-12,15,27H,13-14H2,1-4H3,(H,28,31)
KEGG

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Similars
Article
PubMed
n/an/a 63.1n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human prostanoid EP1 receptor expressed in CHO-K1 cells after 30 mins by topcount liquid scintillation counting

Bioorg Med Chem Lett 21: 4343-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.047
BindingDB Entry DOI: 10.7270/Q2RN394N
More data for this
Ligand-Target Pair