BDBM50419438 CHEMBL1915732

SMILES: FCCn1cc(c(n1)-c1ccc(OCc2cccc(n2)C2CC2)cc1)-c1ccncc1

InChI Key: InChIKey=LQXFYXGYPVHEKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM50419438 (CHEMBL1915732) Show SMILES FCCn1cc(c(n1)-c1ccc(OCc2cccc(n2)C2CC2)cc1)-c1ccncc1 Show InChI InChI=1S/C25H23FN4O/c26-12-15-30-16-23(18-10-13-27-14-11-18)25(29-30)20-6-8-22(9-7-20)31-17-21-2-1-3-24(28-21)19-4-5-19/h1-3,6-11,13-14,16,19H,4-5,12,15,17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag SA Curated by ChEMBL					Assay Description Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...				J Med Chem 54: 5820-35 (2011) Article DOI: 10.1021/jm200536d BindingDB Entry DOI: 10.7270/Q2NV9JNP
					More data for this Ligand-Target Pair