BDBM50420549 CHEMBL2087008
SMILES: COc1ccc(cc1)C(=O)Nc1nnc(s1)-c1ccc(cc1)C(O)=O
InChI Key: InChIKey=DGYUPENFFDJHHX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50420549 (CHEMBL2087008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Competitive inhibition of GST fused human CK2alpha expressed in Escherichia coli BL21 after 10 mins in presence of ATP | J Med Chem 55: 2899-903 (2012) Article DOI: 10.1021/jm2015167 BindingDB Entry DOI: 10.7270/Q2445NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50420549 (CHEMBL2087008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of CK2alpha (unknown origin) using RRRADDSDDDDD as substrate in presence of [gamma33P]-ATP by autoradiography | Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111581 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II alpha' (Homo sapiens (Human)) | BDBM50420549 (CHEMBL2087008) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Competitive inhibition of GST fused human CK2alpha' expressed in Escherichia coli BL21 after 10 mins in presence of ATP | J Med Chem 55: 2899-903 (2012) Article DOI: 10.1021/jm2015167 BindingDB Entry DOI: 10.7270/Q2445NRV | |||||||||||
More data for this Ligand-Target Pair |