BDBM50421591 CHEMBL344294

SMILES: Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1

InChI Key: InChIKey=IJAUTLCFHWJTKE-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50421591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50421591 (CHEMBL344294) Show SMILES Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12-6-7-17-14(10-12)13-4-2-3-5-15(13)20-11-16-18-8-9-19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic, alpha-1B receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled P...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421591 (CHEMBL344294) Show SMILES Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12-6-7-17-14(10-12)13-4-2-3-5-15(13)20-11-16-18-8-9-19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50421591 (CHEMBL344294) Show SMILES Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12-6-7-17-14(10-12)13-4-2-3-5-15(13)20-11-16-18-8-9-19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity of compound towards human Alpha-1B adrenergic receptor expressed in rat fibroblast membranes				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421591 (CHEMBL344294) Show SMILES Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12-6-7-17-14(10-12)13-4-2-3-5-15(13)20-11-16-18-8-9-19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity of compound towards Alpha-1A adrenergic receptor using membranes prepared from Rat-1 fibroblasts expressing human Alpha-1A adrenergi...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50421591 (CHEMBL344294) Show SMILES Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12-6-7-17-14(10-12)13-4-2-3-5-15(13)20-11-16-18-8-9-19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Binding affinity of compound towards human Alpha-1D adrenergic receptor expressed in rat-1 fibroblast membranes				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50421591 (CHEMBL344294) Show SMILES Cc1ccnc(c1)-c1ccccc1OCC1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12-6-7-17-14(10-12)13-4-2-3-5-15(13)20-11-16-18-8-9-19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic, alpha-1D receptor expressed in rat-1 fibroblasts assayed via calcium mobilization through Gq coupled PLC ...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair