BDBM50421596 CHEMBL154023

SMILES: Cc1ncoc1-c1ccccc1NCC1=NCCN1

InChI Key: InChIKey=KUBADPQAWRUMPM-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50421596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421596 (CHEMBL154023) Show SMILES Cc1ncoc1-c1ccccc1NCC1=NCCN1 |t:16| Show InChI InChI=1S/C14H16N4O/c1-10-14(19-9-18-10)11-4-2-3-5-12(11)17-8-13-15-6-7-16-13/h2-5,9,17H,6-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro activation of human alpha-1A receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Adrenergic receptor alpha (Homo sapiens (Human))	BDBM50421596 (CHEMBL154023) Show SMILES Cc1ncoc1-c1ccccc1NCC1=NCCN1 |t:16| Show InChI InChI=1S/C14H16N4O/c1-10-14(19-9-18-10)11-4-2-3-5-12(11)17-8-13-15-6-7-16-13/h2-5,9,17H,6-8H2,1H3,(H,15,16)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro activation of human Alpha-1B receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50421596 (CHEMBL154023) Show SMILES Cc1ncoc1-c1ccccc1NCC1=NCCN1 |t:16| Show InChI InChI=1S/C14H16N4O/c1-10-14(19-9-18-10)11-4-2-3-5-12(11)17-8-13-15-6-7-16-13/h2-5,9,17H,6-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro binding affinity against human Alpha-1D adrenergic receptor expressed in rat-1 fibroblasts				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50421596 (CHEMBL154023) Show SMILES Cc1ncoc1-c1ccccc1NCC1=NCCN1 |t:16| Show InChI InChI=1S/C14H16N4O/c1-10-14(19-9-18-10)11-4-2-3-5-12(11)17-8-13-15-6-7-16-13/h2-5,9,17H,6-8H2,1H3,(H,15,16)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro binding affinity against human Alpha-1B adrenergic receptor expressed in rat-1 fibroblasts				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50421596 (CHEMBL154023) Show SMILES Cc1ncoc1-c1ccccc1NCC1=NCCN1 |t:16| Show InChI InChI=1S/C14H16N4O/c1-10-14(19-9-18-10)11-4-2-3-5-12(11)17-8-13-15-6-7-16-13/h2-5,9,17H,6-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro binding affinity against human Alpha-1A adrenergic receptor expressed in rat-1 fibroblasts cells				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Alpha adrenergic receptor (1a and 1d) (Homo sapiens (Human))	BDBM50421596 (CHEMBL154023) Show SMILES Cc1ncoc1-c1ccccc1NCC1=NCCN1 |t:16| Show InChI InChI=1S/C14H16N4O/c1-10-14(19-9-18-10)11-4-2-3-5-12(11)17-8-13-15-6-7-16-13/h2-5,9,17H,6-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro activation of human alpha-1D receptor expressed in rat-1 fibroblasts via calcium using mobilization through the Gq coupled PLC pathway as fu...				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair