BindingDB logo
myBDB logout

BDBM50422025 CHEMBL103371

SMILES: CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12

InChI Key: InChIKey=CAYIRJBJYNSWEQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422025   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 1d (5-HT1d) receptor


(Sus scrofa)
BDBM50422025
PNG
(CHEMBL103371)
Show SMILES CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12
Show InChI InChI=1S/C17H26N4O2S/c1-19(2)8-7-15-13-18-17-5-4-14(12-16(15)17)6-9-21-11-10-20(3)24(21,22)23/h4-5,12-13,18H,6-11H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 40n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT binding to 5-hydroxytryptamine 1D receptor from pig caudate membrane


J Med Chem 37: 3023-32 (1994)


BindingDB Entry DOI: 10.7270/Q2V69KWJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50422025
PNG
(CHEMBL103371)
Show SMILES CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12
Show InChI InChI=1S/C17H26N4O2S/c1-19(2)8-7-15-13-18-17-5-4-14(12-16(15)17)6-9-21-11-10-20(3)24(21,22)23/h4-5,12-13,18H,6-11H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.51E+3n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]DOB binding to 5-hydroxytryptamine 2A receptor from rat cortex homogenate


J Med Chem 37: 3023-32 (1994)


BindingDB Entry DOI: 10.7270/Q2V69KWJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))
BDBM50422025
PNG
(CHEMBL103371)
Show SMILES CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12
Show InChI InChI=1S/C17H26N4O2S/c1-19(2)8-7-15-13-18-17-5-4-14(12-16(15)17)6-9-21-11-10-20(3)24(21,22)23/h4-5,12-13,18H,6-11H2,1-3H3
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Sharp& Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortex


J Med Chem 37: 3023-32 (1994)


BindingDB Entry DOI: 10.7270/Q2V69KWJ
More data for this
Ligand-Target Pair