BDBM50422266 CHEMBL7019

SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Br)nc1

InChI Key: InChIKey=PBZQPEYJZSYMNV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50422266 (CHEMBL7019) Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Br)nc1 Show InChI InChI=1S/C16H15BrN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-11-9-18-16(17)19-10-11/h3-10,20H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor				J Med Chem 40: 996-1004 (1997) Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT
					More data for this Ligand-Target Pair