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BDBM50422844 CHEMBL440944

SMILES: CN1CCN(CC1)C1C[C@@H](Oc2ccc(Cl)cc2)c2c(C1=O)c1ccccc1n2C

InChI Key: InChIKey=BUBAWRGTUJWAJK-BPGUCPLFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422844   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50422844
PNG
(CHEMBL440944)
Show SMILES CN1CCN(CC1)C1C[C@@H](Oc2ccc(Cl)cc2)c2c(C1=O)c1ccccc1n2C
Show InChI InChI=1S/C24H26ClN3O2/c1-26-11-13-28(14-12-26)20-15-21(30-17-9-7-16(25)8-10-17)23-22(24(20)29)18-5-3-4-6-19(18)27(23)2/h3-10,20-21H,11-15H2,1-2H3/t20?,21-/m1/s1
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Article
PubMed
n/an/a 2.51E+4n/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human recombinant NPY1 receptor expressed in CHO cells

Bioorg Med Chem Lett 16: 1749-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.104
BindingDB Entry DOI: 10.7270/Q2WW7JZG
More data for this
Ligand-Target Pair