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BDBM50422846 CHEMBL426314

SMILES: FC1(F)CCN(CC1)C1C[C@@H](Oc2ccc(Cl)cc2)c2c(C1=O)c1ccccc1n2CC1CCNCC1

InChI Key: InChIKey=QEWJDKVCDFGZSN-WUBHUQEYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422846   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50422846
PNG
(CHEMBL426314)
Show SMILES FC1(F)CCN(CC1)C1C[C@@H](Oc2ccc(Cl)cc2)c2c(C1=O)c1ccccc1n2CC1CCNCC1
Show InChI InChI=1S/C29H32ClF2N3O2/c30-20-5-7-21(8-6-20)37-25-17-24(34-15-11-29(31,32)12-16-34)28(36)26-22-3-1-2-4-23(22)35(27(25)26)18-19-9-13-33-14-10-19/h1-8,19,24-25,33H,9-18H2/t24?,25-/m1/s1
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Article
PubMed
n/an/a 1.86E+3n/an/an/an/an/an/a



GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human recombinant NPY1 receptor expressed in CHO cells

Bioorg Med Chem Lett 16: 1749-52 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.104
BindingDB Entry DOI: 10.7270/Q2WW7JZG
More data for this
Ligand-Target Pair