BindingDB logo
myBDB logout

null

SMILES: COCCCNC(=O)c1sc2nc(C)c(Cl)c(C)c2c1N

InChI Key: InChIKey=CNEXIJQAUMKNPD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423936   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))		BDBM50423936
PNG
(CHEMBL2313372)
Show SMILES COCCCNC(=O)c1sc2nc(C)c(Cl)c(C)c2c1N
Show InChI InChI=1S/C14H18ClN3O2S/c1-7-9-11(16)12(13(19)17-5-4-6-20-3)21-14(9)18-8(2)10(7)15/h4-6,16H2,1-3H3,(H,17,19)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 418n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...

Bioorg Med Chem Lett 23: 346-50 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.073
BindingDB Entry DOI: 10.7270/Q2N29Z8S
More data for this
Ligand-Target Pair