BDBM50423938 CHEMBL2313370

SMILES: Cc1nc2sc(C(=O)NC3CCOCC3)c(N)c2c(C)c1Cl

InChI Key: InChIKey=NIFCIMBMICQYJQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50423938 (CHEMBL2313370) Show SMILES Cc1nc2sc(C(=O)NC3CCOCC3)c(N)c2c(C)c1Cl Show InChI InChI=1S/C15H18ClN3O2S/c1-7-10-12(17)13(22-15(10)18-8(2)11(7)16)14(20)19-9-3-5-21-6-4-9/h9H,3-6,17H2,1-2H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	289	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...				Bioorg Med Chem Lett 23: 346-50 (2012) Article DOI: 10.1016/j.bmcl.2012.10.073 BindingDB Entry DOI: 10.7270/Q2N29Z8S
					More data for this Ligand-Target Pair