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SMILES: Cc1nc2sc(C(=O)NCc3ccncn3)c(N)c2c(C)c1Cl

InChI Key: InChIKey=SEWTXWXXUVSQNS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423956   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))		BDBM50423956
PNG
(CHEMBL2313388)
Show SMILES Cc1nc2sc(C(=O)NCc3ccncn3)c(N)c2c(C)c1Cl
Show InChI InChI=1S/C15H14ClN5OS/c1-7-10-12(17)13(23-15(10)21-8(2)11(7)16)14(22)19-5-9-3-4-18-6-20-9/h3-4,6H,5,17H2,1-2H3,(H,19,22)
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Article
PubMed
n/an/an/an/a 271n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...

Bioorg Med Chem Lett 23: 346-50 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.073
BindingDB Entry DOI: 10.7270/Q2N29Z8S
More data for this
Ligand-Target Pair