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SMILES: Cc1nc2sc(C(=O)NCCc3ccncc3)c(N)c2c(C)c1Cl

InChI Key: InChIKey=HAWNQZRMYJRVQT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423960   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM50423960
PNG
(CHEMBL2313384)
Show SMILES Cc1nc2sc(C(=O)NCCc3ccncc3)c(N)c2c(C)c1Cl
Show InChI InChI=1S/C17H17ClN4OS/c1-9-12-14(19)15(24-17(12)22-10(2)13(9)18)16(23)21-8-5-11-3-6-20-7-4-11/h3-4,6-7H,5,8,19H2,1-2H3,(H,21,23)
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Article
PubMed
n/an/an/an/a 128n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...


Bioorg Med Chem Lett 23: 346-50 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.073
BindingDB Entry DOI: 10.7270/Q2N29Z8S
More data for this
Ligand-Target Pair