BDBM50424415 CHEMBL2315715

SMILES: CN1CC(=O)OB(OC(=O)C1)\C=C\c1ccccc1

InChI Key: InChIKey=OFLDLTAQNBBGGU-BQYQJAHWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50424415 (CHEMBL2315715) Show SMILES CN1CC(=O)OB(OC(=O)C1)\C=C\c1ccccc1 Show InChI InChI=1S/C13H14BNO4/c1-15-9-12(16)18-14(19-13(17)10-15)8-7-11-5-3-2-4-6-11/h2-8H,9-10H2,1H3/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human recombinant BACE using H-RE-(EDANS)EVNLDAEFK(DABCYL)R-OH as substrate preincubated for 1 hr before addition of substrate measured...				Bioorg Med Chem Lett 23: 426-9 (2012) Article DOI: 10.1016/j.bmcl.2012.11.068 BindingDB Entry DOI: 10.7270/Q2MW2JFC
					More data for this Ligand-Target Pair