BDBM50424758 CHEMBL2314200

SMILES: OC(=O)c1[nH]c2ccccc2c1CCCOc1ccc(Cl)c2ccccc12

InChI Key: InChIKey=TZQCEYIFNGTDNS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50424758 (CHEMBL2314200) Show SMILES OC(=O)c1[nH]c2ccccc2c1CCCOc1ccc(Cl)c2ccccc12 Show InChI InChI=1S/C22H18ClNO3/c23-18-11-12-20(16-8-2-1-6-14(16)18)27-13-5-9-17-15-7-3-4-10-19(15)24-21(17)22(25)26/h1-4,6-8,10-12,24H,5,9,13H2,(H,25,26)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...				J Med Chem 56: 15-30 (2013) Article DOI: 10.1021/jm301448p BindingDB Entry DOI: 10.7270/Q29G5P46
					More data for this Ligand-Target Pair