BDBM50425068 CHEMBL2312892

SMILES: CCOC(=O)CNc1ccc2c3C(=O)c4ccccc4-c3n(C)c(=O)c2c1

InChI Key: InChIKey=OMLYGEAZQULWPI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 1 (TDP1) (Homo sapiens (Human))	BDBM50425068 (CHEMBL2312892) Show SMILES CCOC(=O)CNc1ccc2c3C(=O)c4ccccc4-c3n(C)c(=O)c2c1 Show InChI InChI=1S/C21H18N2O4/c1-3-27-17(24)11-22-12-8-9-13-16(10-12)21(26)23(2)19-14-6-4-5-7-15(14)20(25)18(13)19/h4-10,22H,3,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...				J Med Chem 56: 182-200 (2013) Article DOI: 10.1021/jm3014458 BindingDB Entry DOI: 10.7270/Q2MS3V3Z
					More data for this Ligand-Target Pair