BDBM50425134 CHEMBL2313256

SMILES: CCNC(=O)c1ccc2nc(C)c3nnc(-c4cccnc4OC)n3c2c1

InChI Key: InChIKey=QVUMIQCLVPRUBJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM50425134 (CHEMBL2313256) Show SMILES CCNC(=O)c1ccc2nc(C)c3nnc(-c4cccnc4OC)n3c2c1 Show InChI InChI=1S/C19H18N6O2/c1-4-20-18(26)12-7-8-14-15(10-12)25-16(11(2)22-14)23-24-17(25)13-6-5-9-21-19(13)27-3/h5-10H,4H2,1-3H3,(H,20,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 23: 785-90 (2013) Article DOI: 10.1016/j.bmcl.2012.11.077 BindingDB Entry DOI: 10.7270/Q2C82BMR
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50425134 (CHEMBL2313256) Show SMILES CCNC(=O)c1ccc2nc(C)c3nnc(-c4cccnc4OC)n3c2c1 Show InChI InChI=1S/C19H18N6O2/c1-4-20-18(26)12-7-8-14-15(10-12)25-16(11(2)22-14)23-24-17(25)13-6-5-9-21-19(13)27-3/h5-10H,4H2,1-3H3,(H,20,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 23: 785-90 (2013) Article DOI: 10.1016/j.bmcl.2012.11.077 BindingDB Entry DOI: 10.7270/Q2C82BMR
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50425134 (CHEMBL2313256) Show SMILES CCNC(=O)c1ccc2nc(C)c3nnc(-c4cccnc4OC)n3c2c1 Show InChI InChI=1S/C19H18N6O2/c1-4-20-18(26)12-7-8-14-15(10-12)25-16(11(2)22-14)23-24-17(25)13-6-5-9-21-19(13)27-3/h5-10H,4H2,1-3H3,(H,20,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A expressed in Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 23: 785-90 (2013) Article DOI: 10.1016/j.bmcl.2012.11.077 BindingDB Entry DOI: 10.7270/Q2C82BMR
					More data for this Ligand-Target Pair