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SMILES: CCc1cccn1S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=KBZCHSOVUCUOEB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425535   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rap guanine nucleotide exchange factor 4


(Homo sapiens (Human))		BDBM50425535
PNG
(CHEMBL2313642)
Show SMILES CCc1cccn1S(=O)(=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C13H12F3NO2S/c1-2-11-4-3-9-17(11)20(18,19)12-7-5-10(6-8-12)13(14,15)16/h3-9H,2H2,1H3
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Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay

J Med Chem 56: 952-62 (2013)


Article DOI: 10.1021/jm3014162
BindingDB Entry DOI: 10.7270/Q2D21ZX3
More data for this
Ligand-Target Pair