BDBM50425544 CHEMBL2313634

SMILES: Cc1cc(C)c(c(C)c1)S(=O)(=O)c1ccc(OCCN)cc1

InChI Key: InChIKey=DTTCXEZADYIQPM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50425544 (CHEMBL2313634) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)c1ccc(OCCN)cc1 Show InChI InChI=1S/C17H21NO3S/c1-12-10-13(2)17(14(3)11-12)22(19,20)16-6-4-15(5-7-16)21-9-8-18/h4-7,10-11H,8-9,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay				J Med Chem 56: 952-62 (2013) Article DOI: 10.1021/jm3014162 BindingDB Entry DOI: 10.7270/Q2D21ZX3
					More data for this Ligand-Target Pair