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SMILES: Cc1cc(C)c(c(C)c1)S(=O)(=O)c1ccc(OC2CCNCC2)cc1

InChI Key: InChIKey=REYDJSAJBYOGQA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425545   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rap guanine nucleotide exchange factor 4


(Homo sapiens (Human))		BDBM50425545
PNG
(CHEMBL2313633)
Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)c1ccc(OC2CCNCC2)cc1
Show InChI InChI=1S/C20H25NO3S/c1-14-12-15(2)20(16(3)13-14)25(22,23)19-6-4-17(5-7-19)24-18-8-10-21-11-9-18/h4-7,12-13,18,21H,8-11H2,1-3H3
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n/an/a>3.00E+5n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay

J Med Chem 56: 952-62 (2013)


Article DOI: 10.1021/jm3014162
BindingDB Entry DOI: 10.7270/Q2D21ZX3
More data for this
Ligand-Target Pair