BDBM50426286 CHEMBL2312686

SMILES: OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O

InChI Key: InChIKey=RUDCXNDTVSNUGN-RITPCOANSA-N

Data: 3 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50426286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50426286 (CHEMBL2312686) Show SMILES OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c10-7(11)5-2-1-3-9-6(4-5)8(12)13/h5-6,9H,1-4H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	906	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50426286 (CHEMBL2312686) Show SMILES OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c10-7(11)5-2-1-3-9-6(4-5)8(12)13/h5-6,9H,1-4H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50426286 (CHEMBL2312686) Show SMILES OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c10-7(11)5-2-1-3-9-6(4-5)8(12)13/h5-6,9H,1-4H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK2(VCR) receptor expressed in sf9 cells by liquid scintillati...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50426286 (CHEMBL2312686) Show SMILES OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c10-7(11)5-2-1-3-9-6(4-5)8(12)13/h5-6,9H,1-4H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells by [3H]-D-Asp uptake assay				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50426286 (CHEMBL2312686) Show SMILES OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c10-7(11)5-2-1-3-9-6(4-5)8(12)13/h5-6,9H,1-4H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human EAAT3 expressed in HEK293 cells by [3H]-D-Asp uptake assay				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50426286 (CHEMBL2312686) Show SMILES OC(=O)[C@@H]1CCCN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c10-7(11)5-2-1-3-9-6(4-5)8(12)13/h5-6,9H,1-4H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]-D-Asp uptake assay				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair