BDBM50426295 CHEMBL2312397

SMILES: N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O

InChI Key: InChIKey=XNKGBYZPORNNFG-KOLCDFICSA-N

Data: 4 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50426295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	144	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK2(VCR) receptor expressed in sf9 cells by liquid scintillati...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from full length recombinant rat GluKA2(R) receptor expressed in sf9 cells by liquid scintillation counting				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells by [3H]-D-Asp uptake assay				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human EAAT1 expressed in HEK293 cells by [3H]-D-Asp uptake assay				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50426295 (CHEMBL2312397) Show SMILES N[C@@H](C[C@@H](CCC(=O)Nc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C14H18N2O5/c15-11(14(20)21)8-9(13(18)19)6-7-12(17)16-10-4-2-1-3-5-10/h1-5,9,11H,6-8,15H2,(H,16,17)(H,18,19)(H,20,21)/t9-,11+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human EAAT3 expressed in HEK293 cells by [3H]-D-Asp uptake assay				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
					More data for this Ligand-Target Pair