BDBM50426559 CHEMBL2323964

SMILES: Cc1cnc(C)c2nc(nn12)-c1ccn2cc(nc2c1)-c1ccccn1

InChI Key: InChIKey=OBNOZLWMUAPLLI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50426559 (CHEMBL2323964) Show SMILES Cc1cnc(C)c2nc(nn12)-c1ccn2cc(nc2c1)-c1ccccn1 Show InChI InChI=1S/C19H15N7/c1-12-10-21-13(2)19-23-18(24-26(12)19)14-6-8-25-11-16(22-17(25)9-14)15-5-3-4-7-20-15/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of PDE10A (unknown origin) by LE-PDE10A inhibition assay				ACS Med Chem Lett 4: 161-2 (2013) Article DOI: 10.1021/ml4000194 BindingDB Entry DOI: 10.7270/Q2BV7HZR
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50426559 (CHEMBL2323964) Show SMILES Cc1cnc(C)c2nc(nn12)-c1ccn2cc(nc2c1)-c1ccccn1 Show InChI InChI=1S/C19H15N7/c1-12-10-21-13(2)19-23-18(24-26(12)19)14-6-8-25-11-16(22-17(25)9-14)15-5-3-4-7-20-15/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The PDE10 inhibition assay in 384-well plates was conducted to identify substances for the inhibition of cyclic nucleotide hydrolysis by the PDE10 en...				US Patent US8975276 (2015) BindingDB Entry DOI: 10.7270/Q25M64F4
					More data for this Ligand-Target Pair