BDBM50426750 CHEMBL2322159

SMILES: Nc1nccc(n1)-c1ccc(OCc2ccc(F)cc2C(F)(F)F)c(c1)C#N

InChI Key: InChIKey=NLTVRFDWPXDBOB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50426750 (CHEMBL2322159) Show SMILES Nc1nccc(n1)-c1ccc(OCc2ccc(F)cc2C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C19H12F4N4O/c20-14-3-1-12(15(8-14)19(21,22)23)10-28-17-4-2-11(7-13(17)9-24)16-5-6-26-18(25)27-16/h1-8H,10H2,(H2,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Healthcare Limited Curated by ChEMBL					Assay Description Inhibition of bovine xanthine oxidase-mediated uric acid production after 30 mins by spectrophotometric analysis				Bioorg Med Chem Lett 23: 834-8 (2013) Article DOI: 10.1016/j.bmcl.2012.11.057 BindingDB Entry DOI: 10.7270/Q28W3FMN
					More data for this Ligand-Target Pair