BDBM50426769 CHEMBL2322169

SMILES: Nc1nc(cc(=O)[nH]1)-c1ccc(OCc2ccc(F)cc2)c(c1)C#N

InChI Key: InChIKey=ZNOPOVPNRXAYOC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50426769 (CHEMBL2322169) Show SMILES Nc1nc(cc(=O)[nH]1)-c1ccc(OCc2ccc(F)cc2)c(c1)C#N Show InChI InChI=1S/C18H13FN4O2/c19-14-4-1-11(2-5-14)10-25-16-6-3-12(7-13(16)9-20)15-8-17(24)23-18(21)22-15/h1-8H,10H2,(H3,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Healthcare Limited Curated by ChEMBL					Assay Description Inhibition of bovine xanthine oxidase-mediated uric acid production after 30 mins by spectrophotometric analysis				Bioorg Med Chem Lett 23: 834-8 (2013) Article DOI: 10.1016/j.bmcl.2012.11.057 BindingDB Entry DOI: 10.7270/Q28W3FMN
					More data for this Ligand-Target Pair