BDBM50427008 CHEMBL2326864
SMILES: [#6]-[#6](=O)-[#7]-c1nc(-[#6]-[#6]-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])cs1
InChI Key: InChIKey=LMDXCMJWFMSUAI-UHFFFAOYSA-N
Data: 7 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM50427008 (CHEMBL2326864) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a... | Bioorg Med Chem 21: 3873-81 (2013) Article DOI: 10.1016/j.bmc.2013.04.011 BindingDB Entry DOI: 10.7270/Q22B90DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Rattus norvegicus (Rat)) | BDBM50427008 (CHEMBL2326864) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft... | Bioorg Med Chem 21: 3873-81 (2013) Article DOI: 10.1016/j.bmc.2013.04.011 BindingDB Entry DOI: 10.7270/Q22B90DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50427008 (CHEMBL2326864) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human MAOB expressed in CHO cells using benzylamine as substrate after 1 hr by fluorometric assay | Bioorg Med Chem 21: 1219-33 (2013) Article DOI: 10.1016/j.bmc.2012.12.025 BindingDB Entry DOI: 10.7270/Q2K64KDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM50427008 (CHEMBL2326864) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human VAP1 expressed in CHO cells using [14C]-benzylamine as substrate incubated for 30 mins prior to substrate addition measured after... | Bioorg Med Chem 21: 1219-33 (2013) Article DOI: 10.1016/j.bmc.2012.12.025 BindingDB Entry DOI: 10.7270/Q2K64KDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-Amino Acid Oxidase (DAAO) (Rattus norvegicus (rat)) | BDBM50427008 (CHEMBL2326864) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of rat liver DAO using putrescine as substrate after 1 hr by fluorometric assay | Bioorg Med Chem 21: 1219-33 (2013) Article DOI: 10.1016/j.bmc.2012.12.025 BindingDB Entry DOI: 10.7270/Q2K64KDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Rattus norvegicus (Rat)) | BDBM50427008 (CHEMBL2326864) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of rat VAP1 expressed in CHO cells using [14C]-benzylamine as substrate incubated for 30 mins prior to substrate addition measured after 1... | Bioorg Med Chem 21: 1219-33 (2013) Article DOI: 10.1016/j.bmc.2012.12.025 BindingDB Entry DOI: 10.7270/Q2K64KDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50427008 (CHEMBL2326864) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human DAO expressed in CHO cells using putrescine as substrate after 1 hr by fluorometric assay | Bioorg Med Chem 21: 1219-33 (2013) Article DOI: 10.1016/j.bmc.2012.12.025 BindingDB Entry DOI: 10.7270/Q2K64KDW | |||||||||||
More data for this Ligand-Target Pair |