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SMILES: OC(=O)CNC(=O)CNC(=O)COc1ccc2nc3CCCn3c(=O)c2c1

InChI Key: InChIKey=BGFQHCHLBHLYBO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427031   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NEDD8-activating enzyme E1 regulatory subunit


(Homo sapiens (Human))		BDBM50427031
PNG
(CHEMBL2322197)
Show SMILES OC(=O)CNC(=O)CNC(=O)COc1ccc2nc3CCCn3c(=O)c2c1
Show InChI InChI=1S/C17H18N4O6/c22-14(19-8-16(24)25)7-18-15(23)9-27-10-3-4-12-11(6-10)17(26)21-5-1-2-13(21)20-12/h3-4,6H,1-2,5,7-9H2,(H,18,23)(H,19,22)(H,24,25)
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PC cid
PC sid
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Article
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n/an/a 800n/an/an/an/an/an/a



University of Toronto Mississauga

Curated by ChEMBL


Assay Description
Inhibition of NAE (unknown origin)-catalyzed NEDD8-Ubcl2 intermediate formation by densitometric analysis

J Med Chem 56: 2165-77 (2013)


Article DOI: 10.1021/jm301420b
BindingDB Entry DOI: 10.7270/Q29P32ZT
More data for this
Ligand-Target Pair