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SMILES: CN(C)C(=O)Cc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1

InChI Key: InChIKey=PAJURVZXMOOURE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427148   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50427148
PNG
(CHEMBL2323784)
Show SMILES CN(C)C(=O)Cc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1
Show InChI InChI=1S/C22H20N4O2/c1-25(2)21(27)9-14-4-5-15-6-7-20-19(22(28)18(15)8-14)10-16(11-23-20)17-12-24-26(3)13-17/h4-8,10-13H,9H2,1-3H3
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Article
PubMed
n/an/a 1.16E+3n/an/an/an/an/an/a



Merck& Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assay

J Med Chem 56: 2294-310 (2013)


Article DOI: 10.1021/jm301619u
BindingDB Entry DOI: 10.7270/Q21837VX
More data for this
Ligand-Target Pair