BDBM50427160 CHEMBL2324125

SMILES: Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)Nc4ccccc4)cc3c(=O)c2c1

InChI Key: InChIKey=KCVUBAFCQUOASV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50427160 (CHEMBL2324125) Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)Nc4ccccc4)cc3c(=O)c2c1 Show InChI InChI=1S/C25H20N4O3S/c1-29-15-20(14-27-29)19-12-23-24(26-13-19)10-9-18-8-7-17(11-22(18)25(23)30)16-33(31,32)28-21-5-3-2-4-6-21/h2-15,28H,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co., Inc. Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assay				J Med Chem 56: 2294-310 (2013) Article DOI: 10.1021/jm301619u BindingDB Entry DOI: 10.7270/Q21837VX
					More data for this Ligand-Target Pair