BDBM50427166 CHEMBL2324119

SMILES: CNS(=O)(=O)Cc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1

InChI Key: InChIKey=ZITHNZLUOTWYFR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50427166 (CHEMBL2324119) Show SMILES CNS(=O)(=O)Cc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1 Show InChI InChI=1S/C20H18N4O3S/c1-21-28(26,27)12-13-3-4-14-5-6-19-18(20(25)17(14)7-13)8-15(9-22-19)16-10-23-24(2)11-16/h3-11,21H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co., Inc. Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assay				J Med Chem 56: 2294-310 (2013) Article DOI: 10.1021/jm301619u BindingDB Entry DOI: 10.7270/Q21837VX
					More data for this Ligand-Target Pair