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SMILES: Cn1cc(cn1)-c1cnc2ccc3ccc(CC(=O)NCc4ccccn4)cc3c(=O)c2c1

InChI Key: InChIKey=FSWZFTVJPPJUJY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427168   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50427168
PNG
(CHEMBL2324115)
Show SMILES Cn1cc(cn1)-c1cnc2ccc3ccc(CC(=O)NCc4ccccn4)cc3c(=O)c2c1
Show InChI InChI=1S/C26H21N5O2/c1-31-16-20(14-30-31)19-12-23-24(28-13-19)8-7-18-6-5-17(10-22(18)26(23)33)11-25(32)29-15-21-4-2-3-9-27-21/h2-10,12-14,16H,11,15H2,1H3,(H,29,32)
PDB
MMDB

KEGG

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Similars
Article
PubMed
n/an/a 1.37E+3n/an/an/an/an/an/a



Merck& Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assay

J Med Chem 56: 2294-310 (2013)


Article DOI: 10.1021/jm301619u
BindingDB Entry DOI: 10.7270/Q21837VX
More data for this
Ligand-Target Pair