BDBM50427571 CHEMBL2322605

SMILES: Clc1ccc(cc1)N(CC1CNCC1Cc1ccccc1)Cc1ccccc1

InChI Key: InChIKey=IDODFJGRTWMEIV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50427571 (CHEMBL2322605) Show SMILES Clc1ccc(cc1)N(CC1CNCC1Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C25H27ClN2/c26-24-11-13-25(14-12-24)28(18-21-9-5-2-6-10-21)19-23-17-27-16-22(23)15-20-7-3-1-4-8-20/h1-14,22-23,27H,15-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...				J Med Chem 56: 2207-17 (2013) Article DOI: 10.1021/jm3017078 BindingDB Entry DOI: 10.7270/Q2FB5487
					More data for this Ligand-Target Pair