BDBM50428587 CHEMBL2337972

SMILES: COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)c(F)c3F)C(=O)C2(C)C)n2cc(nc12)C(F)(F)F

InChI Key: InChIKey=FJANKXZGXLHESM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50428587 (CHEMBL2337972) Show SMILES COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)c(F)c3F)C(=O)C2(C)C)n2cc(nc12)C(F)(F)F |t:6,18| Show InChI InChI=1S/C28H27F5N6O4/c1-27(2)24(17-8-10-19(42-3)25-34-20(14-38(17)25)28(31,32)33)37-39(26(27)41)12-4-5-13-43-18-9-6-15(22(29)23(18)30)16-7-11-21(40)36-35-16/h6,8-10,14H,4-5,7,11-13H2,1-3H3,(H,36,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PDE3A (unknown origin) by radiochemical assay				Bioorg Med Chem Lett 23: 375-81 (2012) Article DOI: 10.1016/j.bmcl.2012.08.121 BindingDB Entry DOI: 10.7270/Q2B27WNB
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50428587 (CHEMBL2337972) Show SMILES COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)c(F)c3F)C(=O)C2(C)C)n2cc(nc12)C(F)(F)F |t:6,18| Show InChI InChI=1S/C28H27F5N6O4/c1-27(2)24(17-8-10-19(42-3)25-34-20(14-38(17)25)28(31,32)33)37-39(26(27)41)12-4-5-13-43-18-9-6-15(22(29)23(18)30)16-7-11-21(40)36-35-16/h6,8-10,14H,4-5,7,11-13H2,1-3H3,(H,36,40)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin) by radiochemical assay				Bioorg Med Chem Lett 23: 375-81 (2012) Article DOI: 10.1016/j.bmcl.2012.08.121 BindingDB Entry DOI: 10.7270/Q2B27WNB
					More data for this Ligand-Target Pair