BDBM50428593 CHEMBL2337966

SMILES: COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3)C(=O)CC2C)c2cc(nn12)C(F)(F)F

InChI Key: InChIKey=SJIDOEXYZBTNPO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50428593 (CHEMBL2337966) Show SMILES COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3)C(=O)CC2C)c2cc(nn12)C(F)(F)F |t:6,18| Show InChI InChI=1S/C29H30F4N6O4/c1-16-13-23(40)38(37-25(16)19-9-10-24(42-4)39-21(19)15-22(36-39)29(31,32)33)11-5-6-12-43-17-7-8-18(20(30)14-17)26-28(2,3)27(41)35-34-26/h7-10,14-16H,5-6,11-13H2,1-4H3,(H,35,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PDE3A (unknown origin) by radiochemical assay				Bioorg Med Chem Lett 23: 375-81 (2012) Article DOI: 10.1016/j.bmcl.2012.08.121 BindingDB Entry DOI: 10.7270/Q2B27WNB
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50428593 (CHEMBL2337966) Show SMILES COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3)C(=O)CC2C)c2cc(nn12)C(F)(F)F |t:6,18| Show InChI InChI=1S/C29H30F4N6O4/c1-16-13-23(40)38(37-25(16)19-9-10-24(42-4)39-21(19)15-22(36-39)29(31,32)33)11-5-6-12-43-17-7-8-18(20(30)14-17)26-28(2,3)27(41)35-34-26/h7-10,14-16H,5-6,11-13H2,1-4H3,(H,35,41)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PDE4B (unknown origin) by radiochemical assay				Bioorg Med Chem Lett 23: 375-81 (2012) Article DOI: 10.1016/j.bmcl.2012.08.121 BindingDB Entry DOI: 10.7270/Q2B27WNB
					More data for this Ligand-Target Pair