BDBM50428727 CHEMBL2333149

SMILES: Clc1ccc(-[#8]-c2ccc3\[#6](=[#6](/C#N)C#N)-[#6](=O)-c4cccc2c34)cc1

InChI Key: InChIKey=KYXYOAYQWRWUIV-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50428727 (CHEMBL2333149) Show SMILES Clc1ccc(-[#8]-c2ccc3\[#6](=[#6](/C#N)C#N)-[#6](=O)-c4cccc2c34)cc1 Show InChI InChI=1S/C21H9ClN2O2/c22-13-4-6-14(7-5-13)26-18-9-8-16-19(12(10-23)11-24)21(25)17-3-1-2-15(18)20(16)17/h1-9H	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.24E+3	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Binding affinity to his-tagged Mcl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by ITC analysis				Eur J Med Chem 59: 141-9 (2013) Article DOI: 10.1016/j.ejmech.2012.10.050 BindingDB Entry DOI: 10.7270/Q25B03V2
					More data for this Ligand-Target Pair