BDBM50429094 CHEMBL2335783

SMILES: Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1

InChI Key: InChIKey=ZTKJDTUFILTDQB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair