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SMILES: C[C@@H]1c2[nH]c3ccccc3c2Cc2c(O)n(C)c(=S)n12

InChI Key: InChIKey=SZVSYLNMQXFTLS-MRVPVSSYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429152   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM50429152
PNG
(CHEMBL2336691)
Show SMILES C[C@@H]1c2[nH]c3ccccc3c2Cc2c(O)n(C)c(=S)n12 |r|
Show InChI InChI=1S/C15H15N3OS/c1-8-13-10(9-5-3-4-6-11(9)16-13)7-12-14(19)17(2)15(20)18(8)12/h3-6,8,16,19H,7H2,1-2H3/t8-/m1/s1
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Article
PubMed
n/an/a 1.75E+5n/an/an/an/an/an/a



Toho University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant IDO assessed as inhibition of indoleamine 2,3-dioxygenase to kynurenine conversion after 60 mins by HPLC analysis

Bioorg Med Chem 21: 1159-65 (2013)


Article DOI: 10.1016/j.bmc.2012.12.028
BindingDB Entry DOI: 10.7270/Q2RX9DDH
More data for this
Ligand-Target Pair