BDBM50429164 CHEMBL2336692

SMILES: C[C@H]1c2[nH]c3cccc(Br)c3c2Cc2c(O)n(C)c(=S)n12

InChI Key: InChIKey=QNLFRWLMNJVIFU-ZETCQYMHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50429164 (CHEMBL2336692) Show SMILES C[C@H]1c2[nH]c3cccc(Br)c3c2Cc2c(O)n(C)c(=S)n12 |r| Show InChI InChI=1S/C15H14BrN3OS/c1-7-13-8(12-9(16)4-3-5-10(12)17-13)6-11-14(20)18(2)15(21)19(7)11/h3-5,7,17,20H,6H2,1-2H3/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO assessed as inhibition of indoleamine 2,3-dioxygenase to kynurenine conversion after 60 mins by HPLC analysis				Bioorg Med Chem 21: 1159-65 (2013) Article DOI: 10.1016/j.bmc.2012.12.028 BindingDB Entry DOI: 10.7270/Q2RX9DDH
					More data for this Ligand-Target Pair