Found 6 hits for monomerid = 50429233 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Collagenase 3
(Homo sapiens (Human)) | BDBM50429233
(CHEMBL2333287)Show SMILES COc1ccc(C[C@@H](OC(=O)\C=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(O)=O)cc1OC |r| Show InChI InChI=1S/C34H32O8/c1-38-28-16-14-27(20-30(28)39-2)21-32(34(36)37)42-33(35)18-15-24-13-17-29(40-22-25-9-5-3-6-10-25)31(19-24)41-23-26-11-7-4-8-12-26/h3-20,32H,21-23H2,1-2H3,(H,36,37)/b18-15+/t32-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of MMP13 (unknown origin) |
Eur J Med Chem 62: 148-57 (2013)
Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-12 (MMP12)
(Homo sapiens (Human)) | BDBM50429233
(CHEMBL2333287)Show SMILES COc1ccc(C[C@@H](OC(=O)\C=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(O)=O)cc1OC |r| Show InChI InChI=1S/C34H32O8/c1-38-28-16-14-27(20-30(28)39-2)21-32(34(36)37)42-33(35)18-15-24-13-17-29(40-22-25-9-5-3-6-10-25)31(19-24)41-23-26-11-7-4-8-12-26/h3-20,32H,21-23H2,1-2H3,(H,36,37)/b18-15+/t32-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of MMP12 (unknown origin) |
Eur J Med Chem 62: 148-57 (2013)
Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50429233
(CHEMBL2333287)Show SMILES COc1ccc(C[C@@H](OC(=O)\C=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(O)=O)cc1OC |r| Show InChI InChI=1S/C34H32O8/c1-38-28-16-14-27(20-30(28)39-2)21-32(34(36)37)42-33(35)18-15-24-13-17-29(40-22-25-9-5-3-6-10-25)31(19-24)41-23-26-11-7-4-8-12-26/h3-20,32H,21-23H2,1-2H3,(H,36,37)/b18-15+/t32-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP1 catalytic domain using Dnp-Pro-beta-cyclohexyl-Ala-Gly-Cys(Me)-His-Lys-(Nma)-NH2 as substrate preincubated with ... |
Eur J Med Chem 62: 148-57 (2013)
Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50429233
(CHEMBL2333287)Show SMILES COc1ccc(C[C@@H](OC(=O)\C=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(O)=O)cc1OC |r| Show InChI InChI=1S/C34H32O8/c1-38-28-16-14-27(20-30(28)39-2)21-32(34(36)37)42-33(35)18-15-24-13-17-29(40-22-25-9-5-3-6-10-25)31(19-24)41-23-26-11-7-4-8-12-26/h3-20,32H,21-23H2,1-2H3,(H,36,37)/b18-15+/t32-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of MMP3 (unknown origin) |
Eur J Med Chem 62: 148-57 (2013)
Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50429233
(CHEMBL2333287)Show SMILES COc1ccc(C[C@@H](OC(=O)\C=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(O)=O)cc1OC |r| Show InChI InChI=1S/C34H32O8/c1-38-28-16-14-27(20-30(28)39-2)21-32(34(36)37)42-33(35)18-15-24-13-17-29(40-22-25-9-5-3-6-10-25)31(19-24)41-23-26-11-7-4-8-12-26/h3-20,32H,21-23H2,1-2H3,(H,36,37)/b18-15+/t32-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of MMP2 (unknown origin) |
Eur J Med Chem 62: 148-57 (2013)
Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50429233
(CHEMBL2333287)Show SMILES COc1ccc(C[C@@H](OC(=O)\C=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(O)=O)cc1OC |r| Show InChI InChI=1S/C34H32O8/c1-38-28-16-14-27(20-30(28)39-2)21-32(34(36)37)42-33(35)18-15-24-13-17-29(40-22-25-9-5-3-6-10-25)31(19-24)41-23-26-11-7-4-8-12-26/h3-20,32H,21-23H2,1-2H3,(H,36,37)/b18-15+/t32-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of MMP9 (unknown origin) |
Eur J Med Chem 62: 148-57 (2013)
Article DOI: 10.1016/j.ejmech.2012.09.047
BindingDB Entry DOI: 10.7270/Q2VQ341V |
More data for this
Ligand-Target Pair | |
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